Business Card Printing Tips
Free Business Cards Creator

For IE8+ and Firefox:
Go to File, then Page Setup, check the Print Background Colors and Images box, uncheck Enable Shrink to Fit for IE. Under the section labeled Headers and Footers set the top and bottom margins to .5, then the left and right margins to .25. Set all of the Headers and Footers to -Empty- or Blank.

For Internet Explorer 7 and below:
Go to File, then Page Setup find the section labeled Headers and Footers. So you can return it to it's original state copy down on a piece of paper the characters listed under the Header and Footer fields. Then delete all of the characters in the Header and Footer fields. See the first image below as an example of what you may find entered there.

Next you want to set the top and bottom margins to 0.5 and the left and right margins to 0.25. Perforated business card paper usually has 0.5" margins on all sides, the 0.25 side margins allow a little leeway.
View the second image below as an example of how it should look when you are finished.

All Browsers:
Assuming you sized the cards correctly if the margins are set incorrectly when you print the cards you will end up with the cards being down too low on the page and/or the cards cut off on the right side.

If after removing the header and footer and setting the margins the cards print too far up on the paper you can use the Top Margin setting on the Finish page to push it down. A larger number will move them down more than a smaller number.